Triptolide stymies tumor development, extends survival The experts then used triptolide, a known inhibitor of GD3 synthase, to take care of immune-deficient mice injected with breasts cancer tumor cells. Of the mice treated, 50 % didn’t develop breast tumor and the spouse had smaller tumors compared to the control mice. The treated mice lived longer compared to the controls also. GD2’s function in cancer tumor stem cells continues to be unclear. As GD2 can be an immune suppressant, it might be needed by tumor stem cells to counter immune cells during metastases, said first writer Venkata Lokesh Battula, Ph.D., of MD Anderson’s Section of Leukemia.Dr Philippe Mayaud, among Dr Nagot’s colleagues at the LSHTM concludes: ‘Our results have important potential implications for public health and medical practice, as HSV-2 control could become a new type of HIV avoidance targeting HIV-infected individuals, and also providing clinical benefits. Significantly, an HSV vaccine that could either prevent HSV contamination or diminish the medical and sub-scientific manifestations of HSV with a similar efficacy on HIV as HSV suppressive therapy, would represent a long-lasting form of HIV prevention.