Osteoarthritis may be the leading cause of disability in the united kingdom where it affects around six million people. It is a degenerative osteo-arthritis which steadily destroys the cartilage in the joints, particularly in the hands, feet, spine, hips and knees of the elderly. There happens to be no effective treatment other than treatment or joint replacement. Prof Ian Clark, of UEA’s School of Biological Sciences, who is leading the study said: The UK has an aging human population and developing new approaches for combating age-related illnesses such as osteoarthritis is vital – to improve the standard of life for sufferers but also to lessen the financial burden on society. As part of the three-year project, the UEA team will also investigate the consequences of other dietary substances on osteoarthritis, including diallyl disulphide which is found in high amounts in garlic and in addition appears to slow the destruction of cartilage in laboratory models..The researchers discovered that anterior temporal lobe resection would increase life expectancy by 5.0 years, with surgery preferred in 100 % of the simulations, and that resection would increase quality-adjusted life expectancy by 7.5 quality-altered life-years, with surgery chosen in 96.5 % of the simulations. For a 35-year-old patient, the model shows that anterior temporal lobe resection increased the true number of seizure-free years by 15.0 and reduced the life time absolute risk of dying from seizure-related causes by 15 %.